Title

Measuring LRRK2 kinase levels with Sandwich-ELISA in an in vivo viral model of LRRK2-associated Parkinson’s disease.

Creator

Tsiakou, Ifigeneia

Abstract

The project is about the measurement of LRRK2 kinase levels in striatum with Sandwich-ELISA in an in vivo viral model of LRRK2-associated Parkinson’s disease. LRRK2 is a protein, encoded by the LRRK2 gene and the variants of this gene are associated with familial and idiopathic Parkinson’s disease (PD). The importance of LRRK2 levels and their relationship to PD pathogenesis is crucial for understanding underlying mechanisms of the disease and such models are crucial to test new LRRK2-targeted treatments for PD.

Keywords

lrrk2

parkinson’s disease

biomarker

Subject

biomedical sciences

Date Available

June 10, 2024

Type

Poster

Course

BMS 4650 Capstone in Biomedical Sciences

Instructor

Polissidis, Alexia

Session

Poster Display

Location

Student Lounge

Event

Year 2024 | 8th Annual Student Research and Creative Arts Symposium